Research progress of m6A modification in benign ovarian related diseases
10.3969/j.issn.1006-5725.2024.16.024
- VernacularTitle:m6A修饰在良性卵巢相关疾病的研究进展
- Author:
Yanzhi WU
1
;
Yang LIU
Author Information
1. 昆明医科大学第二附属医院生殖医学科(昆明 650000)
- Keywords:
N6-methyladenine;
benign ovarian disease;
polycystic ovary syndrome;
premature ovarian insufficiency;
endometriosis
- From:
The Journal of Practical Medicine
2024;40(16):2352-2356
- CountryChina
- Language:Chinese
-
Abstract:
N6-methyladenine(m6A)modification is involved in a variety of biological processes and dynamically regulates RNA stability.When m6A modification is changed,it affects the development of follicles,granulosa cell proliferation and oocyte development,and participates in the occurrence and development of benign ovaria-related diseases,such as polycystic ovary syndrome,premature ovarian dysfunction,and endometriosis,resulting in decreased female fertility.This article reviews the role and research progress of m6A modification in benign ovaria-related diseases,aiming to provide new diagnosis and treatment ideas for subsequent research on improving fertility.
