Influencing factors of early miscarriage after recurrent spontaneous abortion based on ultrasound endome-trial receptivity parameters and lymphocyte immunophenotype
10.3969/j.issn.1006-5725.2024.10.012
- VernacularTitle:基于超声子宫内膜容受性参数和淋巴细胞免疫表型对复发性流产再孕早期流产的影响因素分析
- Author:
Xiaoying DAI
1
;
Ya SHEN
;
Xiaofang TAN
Author Information
1. 南通市妇幼保健院 超声科(江苏南通 226001)
- Keywords:
recurrent miscarriage;
unknown reasons;
early pregnancy
- From:
The Journal of Practical Medicine
2024;40(10):1402-1406
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influencing factors of pregnancy outcome after re-pregnancy in patients with unexplained recurrent spontaneous abortion based on ultrasound endometrial receptability parameters and lymphocyte immunophenotype.Methods A total of 166 re-pregnant patients with unexplained recurrent spon-taneous abortion admitted to Nantong Maternal and Child Health Hospital from April to August 2022 were included in the study.According to the pregnancy outcome,the patients were divided into the delivery group and the abortion group.The endometrial receptability parameters and peripheral blood T lymphocytes were detected to screen the influencing factors of abortion.Results Among 166 patients,102 cases(61.45%)had successful delivery and 64 cases(38.55%)had abortion again.The delivery group showed thicker endometrial thickness,larger endometrial volume,and higher VFI,but lower CD4+ and CD4+/CD8+ compared to the abortion group(P<0.05).CD4+ and CD4+/CD8+ were observed to be the risk factors for pregnancy failure(P<0.05),and endometrial thickness,endo-metrial volume,and vascularized flow index(VFI)were found to be the protective factors for pregnancy failure(P<0.05).Conclusion The pregnancy outcome of patients with unexplained recurrent spontaneous abortion is related to endometrial thickness,endometrial volume,VFI,CD4+,and CD4+/CD8+.
