Mechanism of T lymphocyte subsets in the malignant transformation of non-alcoholic fatty liver disease
10.3760/cma.j.cn501113-20201029-00586
- VernacularTitle:T淋巴细胞亚群在非酒精性脂肪性肝病恶性转化中的作用机制
- Author:
Wenxin YE
1
;
Ying LIU
;
Xiaoying WANG
;
Dengfu YAO
;
Min YAO
Author Information
1. 南通大学医学院免疫学系,江苏南通 226001
- Keywords:
Non-alcoholic fatty liver disease;
T lymphocyte;
Chronic liver disease;
Cluster of differentiation
- From:
Chinese Journal of Hepatology
2021;29(6):595-599
- CountryChina
- Language:Chinese
-
Abstract:
Nonalcoholic fatty liver disease is becoming the main cause of global liver disease-related morbidity and mortality. Notably, its pathological mechanism is complicated and not yet fully understood. Therefore, immune regulation is undoubtedly an important link in its pathogenesis, especially the change of T lymphocyte subsets. This article introduces the research progress of T lymphocytes involved in steatosis, inflammation, fibrosis, malignant transformation and immunotherapy.