Effect of computerized cognitive training on improving cognitive impairment in patients with dementia: a Meta-analysis
10.3760/cma.j.issn.1674-2907.2017.25.022
- VernacularTitle:计算机辅助认知训练改善痴呆症患者认知障碍效果的Meta分析
- Author:
Chao WANG
1
;
Na LI
;
Fengli MA
Author Information
1. 吉林大学第一医院新生儿科
- Keywords:
Dementia;
Computerized cognitive training;
Cognitive function;
Meta-analysis
- From:
Chinese Journal of Modern Nursing
2017;23(25):3279-3284
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of computerized cognitive training on improving the cognitive impairment in patients with dementia.Methods Literature review was conducted according to the database including PubMed, EMbase, Web of Science, Cochrane Library, CNKI, VIP, CBM and WanFang Data. The research of random control trials (RCTs) that related to CCT and cognitive function published before December 2016 was collected. According to the inclusive and exclusive criteria, two researchers were responsible for extracting data and evaluating the quality of data separately. The meta-analysis was conducted using RevMan 5.3 software.Results A total of nine RCTs were included. The total sample size was 354 and the average age was (75.4±5.24) years old. The literature showed medium quality of data. The meta-analysis showed that the cognitive function scores in patients with CCT were significantly higher than those without CCT intervention (WMD=0.36, 95%CI:0.13-0.58,P=0.002). Patients with CCT also showed significantly better memory function compared with patients without CCT (WMD=0.37, 95%CI: 0.13-0.61, P=0.002). Subgroup analysis showed that CCT could improve the general cognitive function in patients with different degree of dementia but no significant effect was found in patients with vascular dementia (P>0.05). There were no statistically significant effects of CCT on memory function in patients with mild dementia (P>0.05).Conclusions CCT can improve the general cognitive function and memory function in patients with Alzheimer's disease. However, the effect of CCT on cognitive function in patients with vascular dementia and the effect on memory function in patients with mild dementia should be further studied.
