Expression and correlation of CRP and IL-18,IL-37 in gingival crevicular fluid in the subjects treated with invisible correction without bracket and fixed aligners
10.3969/j.issn.1001-3733.2024.06.015
- VernacularTitle:无托槽隐形矫治与固定矫治患者的龈沟液中C反应蛋白与IL-18、IL-37表达及其相关性研究
- Author:
Zhenyu ZHANG
1
;
Yanning MA
;
Bin ZHAO
Author Information
1. 030001 太原,山西医科大学口腔医院正畸科;安徽医科大学附属亳州医院口腔科
- Keywords:
Invisible orthodontics treatment;
Fixed orthodontics treatment;
IL-18;
IL-37;
CRP
- From:
Journal of Practical Stomatology
2024;40(6):823-828
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the expression and correlation of C-reactive protein(CRP)with IL-18,IL-37 in gingival crevic-ular fluid(GCF)after invisible orthodontics treatment and fixed orthodontics treatment respectively.Methods:10 patients with invisible orthodontic treatment were included in the study group,and 12 patients with fixed orthodontic treatment were included in the control group.The expression levels of IL-18,IL-37 and CRP in GCF before,24 h,1 and 3 months after orthodontic treatment were detected by ELISA.Results:Before orthodontic treatment,there was no significant difference in the expression levels of IL-18,IL-37 and CRP in GCF between the 2 groups(P＞0.05).The expression levels of IL-18,IL-37 and CRP in GCF increased at 24 h after treatment,and those in the study group were higher than in the control group(P＜0.05).After 1 month of treatment,those in the study group were low-er than in the control group(P＜0.05).After 3 months of treatment,the expression levels of the factors were not statistically different between the 2 groups(P＞0.05).The leves of CRP,IL-18 and IL-37 in GCF were positivelly correlated in both groups(P＜0.001).Conclusion:The levels of IL-18,IL-37 and CRP in GFC in the subjects treated with invisible correction are increased due to high stress stimulation in a period of 24 hours,suggesting that the effect on the periodontal tissue by the invisible correction may be greater than that by the fixed correction.
