Association between chronic urinary tract infection and primary biliary cirrhosis
10.3760/cma.j.issn.1007-3418.2016.06.019
- VernacularTitle:慢性泌尿系感染与原发性胆汁性肝硬化的关系
- Author:
Yan XU
1
;
Jiangbin WANG
;
Song WANG
Author Information
1. 吉林大学中日联谊医院消化内科
- Keywords:
Primary biliary cirrhosis;
Urinary tract infection;
Risk factors
- From:
Chinese Journal of Hepatology
2016;24(6):478-480
- CountryChina
- Language:Chinese
-
Abstract:
The etiology of primary biliary cirrhosis (PBC) remains unclear,and at present,this disease is considered to be caused by the combined effect of genetic factors,infection,autoimmunity,and environmental factors.Since infection is the major cause for PBC,scholars have been focusing on the association between chronic microbial infection.Studies have shown that Escherichia coli is the most common bacterium for urinary tract infection (UTI),and recurrent UTI has been confirmed to be a risk factor for the development and progression of autoimmune fiver diseases and is closely associated with PBC.This article investigates the association between UTI and PBC and possible mechanisms.
