Molecular mechanism and pathological evaluation strategies for recurrence and metastasis of liver cancer
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1007-3418.2016.05.002
   		
        
        	
        		- VernacularTitle:肝癌复发转移的分子机制与病理学评估策略
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Wenming CONG
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 第二军医大学东方肝胆外科医院病理科
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Carcinoma,hepatocellular;
			        		
			        		
			        		
				        		Neoplasm metastasis;
			        		
			        		
			        		
				        		Pathology;
			        		
			        		
			        		
				        		Diagnosis;
			        		
			        		
			        		
				        		Recurrence;
			        		
			        		
			        		
				        		Mechanism
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Hepatology
	            		
	            		 2016;24(5):324-326
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	The strong invasiveness and metastasis of hepatocellular carcinoma (HCC) are not only the important pathological mechanisms of high recurrence rate and poor long-term outcome,but also the important pathological basis for developing individualized regimens to control metastasis and recurrence in clinical practice.This article introduces the important molecular events in invasion-metastasis cascade discovered in recent years,including the formation mechanism of metastatic niches,methods for molecular pathological evaluation,and standardized pathological diagnosis.