The predictive value of the scoring model of paramedian pontine infarction in early neurological deterioration
10.3969/j.issn.1002-1671.2024.09.004
- VernacularTitle:脑桥旁正中梗死的评分模型预测早期神经功能恶化的价值
- Author:
Yangliu SONG
1
;
Bihua LIU
;
Fang WANG
Author Information
1. 东莞市人民医院放射科,广东 东莞 523058
- Keywords:
paramedian pontine infarction;
early neurological deterioration;
prognosis
- From:
Journal of Practical Radiology
2024;40(9):1413-1416
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the independent risk factors for early neurological deterioration(END)associated with para-median pontine infarction(PPI),to construct a scoring model based on the independent risk factors,and to evaluate its predictive value in END.Methods A total of 163 patients with PPI were retrospectively included and divided into END group(n=35)and non-END group(n=128).After screening possible clinical factors and MRI features,a scoring model was established based on the predictive value,and the predictive efficacy of the model was evaluated.Results Taking END as the endpoint event,homocysteine(Hey)level,maximum infarct size,severe leukoaraiosis(LA),mean apparent diffusion coefficient(ADC)value and inferior pontine infarction were independent risk factors for PPI related END(P＜0.05).Scores were assigned according to odds ratio(OR)value,which were 1,1,3,1,4,respectively,and a scoring model was further established.The model predicted END with an area under the curve(AUC)value of 0.910 and sensitivity of 0.743 and specificity of 0.898 when the score was ≥6 points.Conclusion The scoring model based on Hcy and MRI features has good efficacy in predicting PPI related END,and can provide a basis for prognostic evaluation.
