Application of MR T1-mapping imaging in the quantitative assessment of renal insufficiency in children
10.3969/j.issn.1002-1671.2024.06.019
- VernacularTitle:MR T1-mapping成像在定量评估儿童肾功能不全中的应用
- Author:
Donghao GU
1
;
Jun HU
;
Chuangao YIN
;
Kaixuan WANG
;
Jiajia ZHAO
Author Information
1. 安徽医科大学附属省儿童医院影像科 安徽医科大学第五临床医学院,安徽 合肥 230051
- Keywords:
children;
renal insufficiency;
magnetic resonance imaging;
T1-mapping
- From:
Journal of Practical Radiology
2024;40(6):944-947,1006
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the possibility of MR Ti-mapping imaging technology to provide additional indicators for clinical quantitative evaluation of renal function in children with renal insufficiency.Methods A total of 13 children with renal insufficiency diagnosed and underwent renal function MRI examination were selected(renal insufficiency group),and 23 children with normal renal function were included as the control group.The difference of renal cortex T1 value between the control group and the renal insuffi-ciency group was compared,and the correlation between renal cortex T1 value and biochemical indexes such as serum creatinine(SCr)and cystatin C(CysC)in the renal insufficiency group was analyzed.Results There was significant difference in T1 value of renal cortex between the renal insufficiency group and the control group(P＜0.01).The correlation between T1 value of renal cortex and SCr and CysC in renal insufficiency group was higher(r=0.75,P＜0.01;r=0.68,P＜0.01).Conclusion MR T1-mapping technol-ogy can non-invasively monitor the renal function status of children with renal insufficiency,and has a suggestive value for clinical quantitative evaluation of renal function in children.
