Consensus and controversy on antithyroid drug therapy for Graves′ disease in children and adolescents
10.3760/cma.j.cn101070-20231213-00422
- VernacularTitle:儿童青少年弥漫性毒性甲状腺肿抗甲状腺药物的治疗现状和争议
- Author:
Yang LI
1
;
Chunxiu GONG
Author Information
1. 国家儿童医学中心(北京)，首都医科大学附属北京儿童医院内分泌遗传代谢科，北京 100045
- Keywords:
Thyrotoxicosis;
Graves′ disease;
Treatment;
Antithyroid drug;
Child;
Adolescents
- From:
Chinese Journal of Applied Clinical Pediatrics
2024;39(10):797-800
- CountryChina
- Language:Chinese
-
Abstract:
Graves′ disease (GD) is the most prevalent cause of hyperthyroidism in children, posing a significant threat to their normal growth and development.The incidence of GD is increasing year by year.Antithyroid drugs are the preferred treatment for GD in children, which can alleviate immune disorders and normalize thyroid function in a short period of time.However, there are still numerous unsolved problems and controversies surrounding this treatment, and the challenges that need to be overcome include the low remission rate, high recurrence rate and high incidence of adverse reactions.The key challenges facing antithyroid drug therapy are how to normalize thyroid function quickly, maintain therapeutic efficacy and reduce recurrence rate, and further studies are needed to improve the effectiveness and safety of the therapy.This article summarizes and reviews the therapeutic strategies, controversies and adverse reactions of antithyroid drugs for GD in children and adolescents.
