Research progress on the correlation between premature ovarian insufficiency and autoimmune thyroid disease

VernacularTitle:早发性卵巢功能不全与自身免疫性甲状腺病的相关性研究进展
Author: Zhi-Yun XUE ¹ ; Bin LI ; Xiu-Ying CHEN
Author Information

1. 复旦大学附属妇产科医院妇科上海 200011
Keywords: premature ovarian insufficiency(POI); autoimmune thyroid disease(AITD); pathogenesis
From: Fudan University Journal of Medical Sciences 2024;51(5):820-824
CountryChina
Language:Chinese
Abstract: The incidence of premature ovarian insufficiency(POI)is increasing and showing a trend of affecting younger women,which not only affects women's fertility,but also has the risk of low estrogen in the short and long term.The etiology of POI is complex and highly heterogeneous,including genetic factors,iatrogenic factors,autoimmune dysfunction,infection and environmental factors,but idiopathic POI still accounts for the majority.A lot of researches have focused on the correlation between autoimmune diseases and POI,among which autoimmune thyroid disease(AITD)plays an important role.Therefore,this article will review the current status of POI,the possible pathogenesis of AITD and related treatment progress.