Analysis of therapeutic effect and prognostic factors of intravenous thrombolysis combined with mechanical thrombectomy with Trevo stent in the treatment of ischemic stroke
10.3969/j.issn.1005-6483.2024.05.007
- VernacularTitle:静脉溶栓联合Trevo支架机械取栓治疗缺血性脑卒中的疗效及影响因素分析
- Author:
Yang SUN
1
;
Hao WANG
;
Teng MA
;
Yongji LIU
;
Dan MIAO
;
Ling SHI
Author Information
1. 266033 山东省青岛市中医医院(市海慈医院)青岛大学附属青岛市海慈医院神经内科
- Keywords:
Ischemic stroke;
intravenous thrombolysis;
mechanical thrombectomy;
prognosis;
Influencing factor
- From:
Journal of Clinical Surgery
2024;32(5):468-471
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect and prognostic factors of intravenous thrombolysis combined with Trevo stent mechanical thrombectomy in the treatment of ischemic stroke.Methods A total of 120 patients with ischemic stroke diagnosed and treated in our hospital from January 2020 to December 2022 were selected as research objects and divided into two groups according to random number table method,with 60 cases in each group.Both groups were given basic treatment,the control group was given intravenous thrombolytic therapy,and the observation group was given intravenous thrombolytic therapy combined with mechanical thrombectomy with Trevo stent.The clinical efficacy of the two groups was observed,and the patients were divided into a good prognosis group(46 cases)and a poor prognosis group(74 cases)according to the prognosis.Clinical data such as gender,age,BMI,combined hypertension,combined diabetes,smoking,treatment methods,complete vascular recirculation rate,preoperative NIHSS score and postoperative NIHSS score of the two groups were collected.The independent prognostic factors were analyzed by univariate and multivariate binary Logistic regression.Results The total effective rate of the study group was significantly higher 88.33％(53/60)than that of the control group 73.33％(44/60),and the difference was statistically significant(P＜0.05).Univariate analysis showed that there were no statistically significant differences in gender,BMI,diabetes mellitus,and preoperative NIHSS score between the two groups(P＞0.05),while there were statistically significant differences in age,hypertension,smoking,treatment style,complete vascular revasculosity,and postoperative NIHSS score between the two groups(P＜0.05).Logistic regression analysis showed that age,treatment style and complete vascular revasculopathy rate were independent factors affecting the prognosis of ischemic stroke patients(P＜0.05).Conclusion Intravenous thrombolysis combined with mechanical thrombectomy with Trevo stent can improve the clinical efficacy and prognostic quality of ischemic stroke patients in the time window of intravenous thrombolysis.In addition,the prognosis of patients with ischemic stroke is also closely related to the age of patients and the rate of complete vascular recirculation after surgery.
