Research progress of cuproptosis in the treatment and prognosis of oral squamous cell carcinoma
10.13591/j.cnki.kqyx.2024.11.014
- VernacularTitle:铜死亡在口腔鳞状细胞癌治疗及预后中的研究进展
- Author:
Tian YAO
1
;
Yufeng MA
Author Information
1. 山西医科大学口腔医学院,山西 太原(030000)
- Keywords:
oral squamous cell carcinoma;
cuproptosis;
ferredoxin 1;
protein lipids;
copper chelates;
lncRNA;
tricarboxylic acid cycle
- From:
STOMATOLOGY
2024;44(11):871-875
- CountryChina
- Language:Chinese
-
Abstract:
Oral squamous cell carcinoma(OSCC)is a malignant tumor with a high mortality rate,which is characterized by late diag-nosis,high recurrence and metastasis rates,and poor prognosis.Cuproptosis,as a novel mode of cupric induced cell death,can inhibit the growth and proliferation of cancer cells by activating related pathways,which provides a new insight into the treatment of OSCC.This review aims to systematically introduce the mechanism of cuproptosis occurrence and development,as well as the research progress of cuproptosis in the prognosis of OSCC treatment.It provides new ideas and methods for clinical treatment.
