The clinical effect of biomimetic salivary gland induction technique in alleviating secondary xerostomia after endovascular intervention of isolated superior mesenteric artery dissection
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3969/j.issn.1008-794X.2024.11.015
   		
        
        	
        		- VernacularTitle:孤立性肠系膜上动脉夹层腔内介入术后应用仿生唾液腺诱导技术缓解继发口干症的效果研究
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yan LI
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Jingping GE
			        		
			        		;
		        		
		        		
		        		
			        		Yuanyuan YIN
			        		
			        		;
		        		
		        		
		        		
			        		Hongxia SUN
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 210001 江苏南京 南京医科大学附属南京医院(南京市第一医院)介入血管科
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		biomimetic salivary gland induction technology;
			        		
			        		
			        		
				        		isolated superior mesenteric artery dissection;
			        		
			        		
			        		
				        		interventional treatment;
			        		
			        		
			        		
				        		xerostomia
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Journal of Interventional Radiology
	            		
	            		 2024;33(11):1229-1233
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	Objective To discuss the clinical effect of biomimetic salivary gland induction technology in alleviating secondary xerostomia after endovascular intervention of isolated superior mesenteric artery dissection(ISMAD).Methods Using random number sampling method,a total of 80 patients with ISMAD,who received endovascular intervention at the Affiliated Nanjing Hospital of Nanjing Medical University of China between March 2020 and December 2022,were selected as the research subjects.For the patients of control group(n=40)the warm-water(25-35 ℃)cotton swab was adopted to moisten the lips from one hour to 48 hours after endovascular intervention,which was given once every 15 minutes within postoperative 1-2 hours,which was followed by once every 30 minutes within postoperative 3-48 hours.For the patients of study group(n=40)with the help of biomimetic salivary gland induction technology a continuous and controlled water flow at a rate of 15 mL/h was given from one hour to 48 hours after endovascular intervention to continuously keep the lips and mouth moist.The postoperative one-,12-,24-and 48-hour degrees of mouth dryness and oral comfort in both groups were analyzed.Results The postoperative one-,12-,24-,and 48-hour incidence of thirsty and the degrees of severity in the study group were significantly lower than those in the control group(all P<0.01),and the degrees of oral comfort at postoperative different time points in the study group were remarkably better than those in the control group(all P<0.01).Conclusion The use of biomimetic salivary gland induction technology in patients with ISMAD after receiving endovascular intervention therapy can significantly reduce the incidence and severity of thirsty and improve oral comfort.