Research Progress in the Treatment of Depression by Baihe Dihuang Decoction and Its Associated Formulas
10.13359/j.cnki.gzxbtcm.2024.11.038
- VernacularTitle:百合地黄汤及其类方治疗抑郁症的研究进展
- Author:
Feng-Xiang DAI
1
;
Hai-Bin HUANG
Author Information
1. 广州中医药大学第三附属医院,广东 广州 510378
- Keywords:
depression;
Baihe Dihuang Decoction;
Baihe Zhimu Decoction;
Baihe Jizi Decoction;
internal heat due to yin deficiency;
monoamine neurotransmitters;
inflammatory response;
neurons;
review
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2024;41(11):3078-3083
- CountryChina
- Language:Chinese
-
Abstract:
Baihe Dihuang Decoction is a classic formula recorded in Jin Gui Yao Lve(Synopsis of the Golden Chamber),which has the actions of nourishing yin and clearing heat,tonifying heart and lung.Baihe Dihuang Decoction and its associated formulas are widely used for the treatment of depression,insomnia,women's menopausal syndrome and other psychiatric disorders.This article retrieved the relevant literature about Baihe Dihuang Decoction and its associated formulas such as Baihe Zhimu Decoction and Baihe Jizi Decoction for the treatment of depression in recent years,and analyzed the clinical application and the possible pharmacological mechanisms of Baihe Dihuang Decoction and its associated formulas for the treatment of depression.The analysis showed that Baihe Dihuang Decoction and its associated formulas were indicated for the patients with internal heat due to yin deficiency syndrome,and their antidepressive mechanism is related to up-regulating the levels of monoamine neurotransmitters and the expression of brain-derived neurotrophic factors,inhibiting inflammatory responses,protecting neurons and regulating energy metabolism.The analysis results for the clinical application and possible therapeutic mechanism of Baihe Dihuang Decoction and its associated formulas in counteracting depression will provide reference for the clinical treatment and basic research of depression.
