Study on Traditional Chinese Medicine Syndrome Elements of Inpatients with Primary Sjogren's Syndrome
10.13359/j.cnki.gzxbtcm.2024.10.029
- VernacularTitle:原发性干燥综合征住院患者的中医证素研究
- Author:
Guo-Yan LI
1
;
Yi-Ting HE
Author Information
1. 广州中医药大学第二临床医学院,广东广州 510405
- Keywords:
primary Sjogren's syndrome(pSS);
dryness blockage syndrome;
syndrome elements;
liver;
lung;
yin deficiency;
qi deficiency;
traditional Chinese medicine(TCM)syndrome types;
deficiency of qi and yin
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2024;41(10):2713-2719
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distribution patterns of traditional Chinese medicine(TCM)syndrome elements in patients with primary Sjogren's syndrome(pSS;dryness blockage syndrome in TCM).Methods A total of 240 inpatients with pSS who met the inclusion and exclusion criteria and were treated in Guangdong Provincial Hospital of Chinese Medicine from January 2012 to December 2022 were selected as the research objects,and data mining was performed on the information of syndrome elements.Results(1)Among the 240 patients,there were 21 males(accounting for 8.75％)and 219 females(accounting for 91.25％),indicating that most of which were female patients.In terms of the age,33(13.75％)patients were young(18-45 years old),148(61.67％)patients were middle-aged(46-69 years old),and 59(24.58％)patients were elderly(being or over 70 years old),indicating that most of the patients were middle-aged.(2)Among 240 patients,4 cases had no manifestations of any syndrome elements,and a total of 38 syndrome elements were obtained from the 236 cases of patients,including 15 diseases-location syndrome elements and 23 diseases-nature syndrome elements.The total frequency of syndrome elements was 1 142 times.The leading diseases-location syndrome elements with high frequency were liver(6.04％),lung(4.99％)and bones(4.20％),and the leading diseases-nature syndrome elements with high frequency were yin deficiency(13.75％),qi deficiency(9.37％)and phlegm(6.57％).The diseases-location syndrome elements were predominated by the single syndrome elements of disease-location(42.92％),and the diseases-nature syndrome elements were predominated by the complex syndrome elements of over five kinds of diseases-nature(25.83％).There were significant differences in the distribution of spleen and yin deficiency syndrome elements between the males and the females(P＜0.05),and statistically significant differences were shown in the distribution of qi deficiency and fluid retention syndrome elements among various age groups(P＜0.05).The syndrome-element combinations with high frequency were qi deficiency+yin deficiency(72 times,30％)and phlegm-damp+yin deficiency(72 times,30％),and then came heat+yin deficiency(59 times,24.58％).The analysis of the combination of syndrome elements showed that the common TCM syndrome types of 240 cases of pSS were deficiency of qi and yin,yin deficiency and phlegm-damp,and yin deficiency with flaring of fire.Conclusion The affection of pSS often involves the liver and lung.In the patients with pSS,yin deficiency and qi deficiency are the most common syndrome elements,and the syndrome elements are usually complex;deficiency of qi and yin is the common type of syndrome.The results indicated that the differentiation and treatment of pSS starting from the syndrome elements will be more targeted.
