Progress of platelet-rich fibrin in chronic wound applications
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.cn115396-20240702-00206
   		
        
        	
        		- VernacularTitle:富血小板纤维蛋白在慢性创面应用中的进展
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Tonghan LI
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Dongfang WANG
			        		
			        		;
		        		
		        		
		        		
			        		Hong ZHAO
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 华中科技大学同济医学院附属同济医院创伤外科,武汉 430030
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Platelet-rich plasma;
			        		
			        		
			        		
				        		Platelet-rich fibrin;
			        		
			        		
			        		
				        		Chronic wounds;
			        		
			        		
			        		
				        		Ulcer;
			        		
			        		
			        		
				        		Wound healing
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			International Journal of Surgery
	            		
	            		 2024;51(11):773-779
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Chronic wounds are chronic diseases with various causes, complex pathogenesis, prolonged disease and seriously affecting the quality of life of patients. Routine surgical treatment is often not effective, causing huge economic burden to patients′ individuals, families and society. In recent years, with the deepening of research, the application of platelet-rich fibrin (PRF) in chronic wound treatment has attracted more and more attention at home and abroad. This paper aims to review the development of PRF, analyzing the underlying mechanisms of promoting chronic wound healing, and deeply explore its practical application in various types of chronic wound treatment, in order to provide new ideas and strategies for the treatment field of chronic wound.