Progress on neonatal hypoglycemia and related brain injury

VernacularTitle:新生儿低血糖及其脑损伤的研究进展
Author: Tingwei ZHANG ¹ ; Ziyu HUA
Author Information

1. 重庆医科大学附属儿童医院新生儿科　国家儿童健康与疾病临床医学研究中心　儿童发育疾病研究教育部重点实验室　儿童感染与免疫罕见病重庆市重点实验室400014
Keywords: Infant，newborn; Hypoglycemia; Hypoglycemic brain damage; Mechanism
From: International Journal of Pediatrics 2024;51(10):685-688
CountryChina
Language:Chinese
Abstract: Neonatal hypoglycemia is one of the most common metabolic conditions in newborns.A considerable proportion of newborns are evaluated to be at risk of hypoglycemia，and transitional hypoglycemia is common in healthy newborns.A correlation between severe and prolonged hypoglycemia and neonatal hypoglycemic brain damage（HBD）in newborns has been proven.Factors such as hypoglycemia，glucose reperfusion，and blood glucose fluctuations are all involved in the damage process of HBD to a certain extent.This article reviews the relevant definitions of neonatal hypoglycemia，the characteristics of neonatal blood glucose metabolism，the related mechanisms of HBD，and possible treatment strategies to improve its prognosis.