Advance in ABCC4 and related diseases
10.3760/cma.j.issn.1673-4408.2024.09.009
- VernacularTitle:ABCC4蛋白与相关疾病的研究进展
- Author:
Wei LI
1
;
Yanyan LIANG
;
Hua ZHU
Author Information
1. 内蒙古医科大学，呼和浩特 010020
- Keywords:
ABCC4;
Bronchial asthma;
Acute lung injury;
Kawasaki disease;
Mechanism
- From:
International Journal of Pediatrics
2024;51(9):616-620
- CountryChina
- Language:Chinese
-
Abstract:
ATP-binding cassette subfamily C member 4（ABCC4），a member of ATP-binding cassette transporter C subfamily，is involved in extracellular signaling pathways and cellular protection.As a multifunctional transporter protein，ABCC4 is prevalently present in multiple cells of the human body，and is capable of pumping out a variety of endogenous and exogenous substances from cells.It is closely related to the occurrence and development of multifarious diseases，and is also a potential therapeutic target for many diseases.The structure，function and related research progress of ABCC4 in a large amount of systemic diseases are reviewed.
