Advances in the treatment of IgA nephropathy
10.3760/cma.j.issn.1673-4408.2024.08.006
- VernacularTitle:IgA肾病治疗进展
- Author:
Yuan XU
1
;
Fang DENG
Author Information
1. 安徽省儿童医院肾内科，合肥 230051
- Keywords:
Children;
IgA nephropathy;
Supportive treatment;
Targeted therapy
- From:
International Journal of Pediatrics
2024;51(8):528-531
- CountryChina
- Language:Chinese
-
Abstract:
IgA nephropathy（IgAN）is the most common cause of glomerular hematuria in China.It is the most common primary glomerular disease in the world，mainly characterized by recurrent gross hematuria or microscopic hematuria and IgA deposition in the mesangial region.The early symptoms of IgAN are mild and the onset is insidious，with slowly progress and eventually about 40% to end-stage renal disease.So far，the pathogenesis of IgAN is not fully understood and its clinical and pathological manifestations are diverse.At present，supportive treatment is the main treatment and there is a lack of specific and effective treatment.In this paper，the therapeutic progress of IgAN will be reviewed from the aspects of supportive therapy，hormone drugs，immunosuppressants，antimalarial drugs and novel biologics.
