Research Progress on Detection of New Psychoactive Substance Piperazines in vivo
10.12116/j.issn.1004-5619.2023.330802
- VernacularTitle:哌嗪类新精神活性物质体内检测研究进展
- Author:
Jin-Ting LIU
1
;
Li-Ying ZHOU
;
Jia-Hong XIANG
;
Zi-Yi LI
;
Wan-Ting XIE
;
Ke-Ming YUN
;
Yan SHI
Author Information
1. 司法鉴定科学研究院 上海市法医学重点实验室 司法部司法鉴定重点实验室 上海市司法鉴定专业技术服务平台,上海 200063;山西医科大学法医学院,山西 晋中 030600
- Keywords:
forensic toxicology;
new psychoactive substances;
piperazines;
in vivo;
high performance liquid chromatography;
gas chromatography-tandem mass spectrometry;
liquid chromatography-mass spectrometry;
review
- From:
Journal of Forensic Medicine
2024;40(3):276-283
- CountryChina
- Language:Chinese
-
Abstract:
Piperazines are a class of new psychoactive substances with hallucinogenic effects that af-fect the central nervous system by affecting the level of monoamine neurotransmitters.Abuse of pipera-zines will produce stimulating and hallucinogenic effects,accompanied by headache,dizziness,anxiety,insomnia,vomiting,chest pain,tachycardia,hypertension and other adverse reactions,and may even cause cardiovascular diseases and multiple organ failure and lead to death,seriously affecting human physical and mental health and public safety.The abuse of new psychoactive substance piperazines has attracted extensive attention from the international community.The study of its pharmacological toxi-cology and analytical methods has become a research hotspot in the field of forensic medicine.This paper reviews the in vivo processes,sample treatment and analytical methods of existing piperazines,in order to provide reference for forensic identification.
