Anti-adhesion/Photothermal Bactericidal Surface Based on a Looped Polyzwitterion
10.19756/j.issn.0253-3820.241093
- VernacularTitle:基于环状构象两性离子聚合物的抗粘附/光热杀菌表面性能分析
- Author:
Xiao-Yu XIA
1
;
Guang-Yu ZHANG
;
Zhao-Hui SU
Author Information
1. 中国科学院长春应用化学研究所,高分子物理与化学国家重点实验室,长春 130022;中国科学技术大学应用化学与工程学院,合肥 230026
- Keywords:
Photothermal sterilization;
Antibacterial surfaces;
Loop conformation;
Antifouling coatings;
Silver nanoparticles
- From:
Chinese Journal of Analytical Chemistry
2024;52(5):717-724
- CountryChina
- Language:Chinese
-
Abstract:
Infections caused by drug-resistant bacteria attaching to medical devices pose significant challenges to public health,and as such development of anti-adhesion and bactericidal surfaces with long-term performance is of practical importance.In this study,polydopamine(PDA),silver nanoparticles(AgNPs)and PDA were sequentially deposited on the glass substrate,and then polysulfobetaine methacrylate(PSBMA),a zwitterionic polymer,with a loop conformation was grafted onto the PDA surface to construct PAP-PSBMA-loop,a dual-functional antibacterial coating combining bacterial adhesion-resistance and photothermal sterilization properties.Due to the robust antifouling ability of the zwitterionic polymer and the excellent photothermal conversion ability of PDA and AgNPs,PAP-PSBMA-loop coating demonstrated excellent resistance to bacterial adhesion and sterilization performance under near-infrared(NIR)irradiation.After 7 days of incubation with bacteria,the coating surface exhibited a low bacterial coverage of 1.7%,and was able to suppress biofilm formation effectively and kill>99%of the bacteria that managed to adhere upon exposure to NIR irradiation.
