Application of non-coding RNA and proteomics in radiation biodosimetry
10.16781/j.CN31-2187/R.20230108
- VernacularTitle:非编码RNA和蛋白质组学在辐射生物剂量学中的应用
- Author:
Xingyu LIU
1
;
Tao WANG
;
Changjing ZUO
;
Jianming CAI
Author Information
1. 海军军医大学(第二军医大学)海军医学系,上海 200433;温州医科大学公共卫生与管理学院,温州 325035;海军军医大学(第二军医大学)第一附属医院核医学科,上海 200433
- Keywords:
ionizing radiation;
radiation biodosimetry;
radiation biomarkers;
non-coding RNA;
proteomics
- From:
Academic Journal of Naval Medical University
2024;45(12):1540-1545
- CountryChina
- Language:Chinese
-
Abstract:
An ideal ionizing radiation biomarker should be able to quickly,conveniently and accurately assess the radiation dose received by individuals,and can predict the effect of radiation-induced damage.Radiation dose assessment based on gene or molecular expression profiles is a research focus in the field of radiation biodosimetry.Non-coding RNA and proteomics have the characteristic of high-throughput that allows for rapid and real-time detection,making them highly potential for radiation biodosimetry research.This paper summarizes the research progress of non-coding RNA and proteins as potential radiation biomarkers in recent years,and also reviews their influencing factors and application scenarios.
