Value of NLR,PLR and LMR in early diagnosis of influenza A viral pneumonia
10.3969/j.issn.1671-8348.2024.21.008
- VernacularTitle:NLR、PLR、LMR在甲型流感病毒性肺炎早期诊断中的价值
- Author:
Lijiang FANG
1
;
Lu YUAN
;
Xingjun GAO
;
Qian ZHANG
;
Yi ZHANG
Author Information
1. 陕西中医药大学第二附属医院检验科,陕西咸阳 712099
- Keywords:
neutrophil to lymphocyte ratio;
platelet to lymphocyte ratio;
lymphocyte to monocyte rati-o;
viral pneumonia;
diagnostic value
- From:
Chongqing Medicine
2024;53(21):3240-3244
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical value of neutrophil to lymphocyte ratio(NLR),platelet to lymphocyte ratio(PLR)and lymphocyte to monocyte ratio(LMR)in the early diagnosis of influenza A viral pneumonia.Methods The patients with pneumonia receiving treatment in this hospital from June 2020 to June 2023 were selected as the study subjects and divided into the influenza A viral pneumonia group(viral group,n=60),bacterial pneumonia group(bacterial group,n=60)and mycoplasma pneumonia group(myco-plasma group,n=55)according to the pathogenic diagnostic results.Fifty healthy subjects undergoing physi-cal examination at the same time were selected as the control group(n=50).The differences in NLR,PLR and LMR were compared among the four groups,and the sensitivity and specificity of NLR,PLR and LMR in the diagnosis of viral pneumonia were analyzed.Results Compared with the control group,the levels of NLR,PLR and LMR in the bacterial group,viral group and mycoplasma group were higher(P＜0.05),moreover the LMR level in the viral group was higher than that in the bacterial group and mycoplasma group,and the differences were statistically significant(P＜0.05).The logistic regression model results showed that the higher the NLR,PLR and LMR levels,which prompted that the greater the likelihood of virus infection(P＜0.05).For every unit increase in NLR,the risk of virus infection was increased by 1.003 times;for every unit increase in PLR,the risk of virus infection was increased by 1.163 times;for every unit increase in LMR,the risk of virus infection was increased by 1.036 times.The receiver operating characteristic(ROC)curve results showed that the areas under the curves(AUC)of NLR,PLR and LMR single detection were＞0.5,AUC of the three combination was 0.880,the sensitivity was 71.4％and the specificiry was 74.9％.Conclusion The combination of NLR,LMR and PLR could be used to diagnose influenza A viral pneumonia.
