Research progress on genetic etiology and prenatal diagnosis method of congenital heart disease
10.3969/j.issn.1671-8348.2024.20.021
- VernacularTitle:先天性心脏病的遗传学病因及产前诊断方法的研究进展
- Author:
Tingxue HAN
1
;
Dongmei LI
Author Information
1. 昆明理工大学附属医院/云南省第一人民医院医学遗传科/国家卫生健康委西部优生与出生缺陷防控重点实验室,昆明 650100;昆明理工大学医学院,昆明 650000
- Keywords:
fetus;
congenital heart disease;
prenatal diagnosis;
genetic techniques;
review
- From:
Chongqing Medicine
2024;53(20):3161-3167
- CountryChina
- Language:Chinese
-
Abstract:
Congenital heart disease(CHD)is the most common birth defect in China.At present,the pathogenesis of CHD is still unclear,most of its prenatal diagnostic methods are single ultrasound diagnosis with limited clinical value.Standardized and systematic prenatal diagnostic methods are of great significance to the prevention and control of CHD.This paper outlines the etiology of CHD,elaborates the prenatal diagnostic methods of CHD from the aspects of imaging,cytogenetics,serology and molecular biology,at the same time briefly introduces the cutting-edge detection technologies and intrauterine treatment related contents and ex-plores the current existing problems to provide reference for clinical prenatal diagnosis of fetus.
