Research progress on biomarkers related to aggressiveness in pituitary neuroendocrine tumors
10.3969/j.issn.1671-8348.2024.19.026
- VernacularTitle:垂体神经内分泌肿瘤侵袭性相关生物标志物的研究进展
- Author:
Gang ZHANG
1
;
Chuan SHAO
;
Nan WU
Author Information
1. 重庆医科大学,重庆 400016;重庆市人民医院神经外科,重庆 401147
- Keywords:
pituitary neuroendocrine tumors;
invasive;
biomarkers;
subtype;
review
- From:
Chongqing Medicine
2024;53(19):3024-3028
- CountryChina
- Language:Chinese
-
Abstract:
Reliable biomarkers are very important for early diagnosis,effective treatment and prognos-tic assessment of aggressive pituitary neuroendocrine tumors(PitNETs).With the accumulation of resear-ches,the occurrence and development of PitNETs have been better understood,and many biomolecules that can participate in the aggressive growth of PitNETs have been reported.However,due to the large heterogene-ity among the subtypes of PitNETs and the involvement of multi-dimensional and highly complex regulatory networks,there are still very few biomarkers that can be applied to clinical diagnosis and treatment.This arti-cle reviews the biomarkers related to the invasiveness of PitNETs,further elaborates the mechanism behind the invasiveness of PitNETs,and provides the ideas for finding the target spots for the diagnosis,treatment and prognosis evaluation of PitNETs.
