Analysis on risk factors of severe acute pancreatitis complicating splanchnic venous thrombosis
10.3969/j.issn.1671-8348.2024.08.010
- VernacularTitle:重症急性胰腺炎并发内脏静脉血栓的危险因素分析
- Author:
Qi TANG
1
;
Na LUO
;
Bingqiang ZHANG
Author Information
1. 重庆医科大学附属第一医院消化内科,重庆 400016
- Keywords:
severe acute pancreatitis;
pancreatic cyst;
splanchnic vein thrombosis;
risk factors;
APACHE Ⅱ score
- From:
Chongqing Medicine
2024;53(8):1173-1178
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors of complicating splanchnic venous thrombosis (SVT) in severe acute pancreatitis (SAP) in order to guide clinic for conducting early prevention.Methods A total of 173 patients with SAP admitted and treated in this hospital from January 2018 to December 2022 were selected and divided into the non-complicating SVT group (n=143) and complicating SVT group (n=30) ac-cording to whether having secondary SVT or not.The general data and various clinical treatment and examina-tion-related data were collected.The multi-factor logistic regression was used to analyze the risk factors of complicating SVT in SAP.Results Shock (P<0.001),pancreatic cyst (P=0.002),tracheal intubation (P<0.001),proportion of abnormal renal function (P=0.014),total bilirubin (P=0.049),direct bilirubin (P=0.018),AST (P=0.011),procalcitonin (P=0.021),thrombin time (P=0.024),D-dimer (P=0.003),MCTSI score (P<0.001) and APACHE Ⅱ score (P<0.001) had statistical difference between the two groups.The multivariate logistic regression analysis showed that pancreatic cyst (OR=2.700,95％CI:1.022-7.134,P=0.045) and APACHE Ⅱ score increase (OR=1.137,95％CI:1.002-1.290,P=0.047) were the independent risk factors for complicating SVT in SAP.Conclusion Pancreatic cysts and APACHE Ⅱ score increase are the independent risk factors for complicating SVT in SAP.These patients require close fol-low-up and timely intervention and treatment.
