Research pregress in pain matrix of postherpetic neuralgia
10.13481/j.1671-587X.20240335
- VernacularTitle:带状疱疹后遗神经痛疼痛矩阵的研究进展
- Author:
Qiuping LIU
1
;
Tao LIU
;
Xuezhu ZHANG
Author Information
1. 天津中医药大学第一附属医院针灸研究所,天津 300193;国家中医针灸临床医学研究中心,天津 300193
- Keywords:
Postherpetic neuralgia;
Pain matrix;
Brain region;
Certral nervous system;
Pain syndrome
- From:
Journal of Jilin University(Medicine Edition)
2024;50(3):872-880
- CountryChina
- Language:Chinese
-
Abstract:
Postherpetic neuralgia(PHN)is a typical chronic neuropathic pain syndrome.Both peripheral and central nervous system mechanisms are believed to be involved in PHN,but the central nervous system-related brain network structure and function are not yet fully elucidated,limiting the study on the clinical analgesic drugs and other intervention strategies.In recent years,the research on pain matrix-related brain networks has helped to reveal the central nervous system regulation mechanism of pain,but there are few reports on the PHN pain matrix.This review summarizes the recent studies on the PHN pain matrix,retrospectively analyzes the functional and structural changes in specific pain-related brain regions,in order to provide the new insights for exploring the effective targeted analgesic treatments.
