A Case of Latent Autoimmune Diabetes in Adults Developed after Surgical Cure of Growth Hormone Secreting Pituitary Tumor.
10.3803/EnM.2012.27.4.318
- Author:
Wonjin KIM
1
;
Jung Ho KIM
;
Youngsook KIM
;
Ji Hye HUH
;
Su Jin LEE
;
Mi Sung PARK
;
Eun Yeong CHOE
;
Jeong Kyung PARK
;
Myung Won LEE
;
Jae Won HONG
;
Byung Wan LEE
;
Eun Seok KANG
;
Bong Soo CHA
;
Eun Jig LEE
;
Hyun Chul LEE
Author Information
1. Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. edgo@yuhs.ac
- Publication Type:Case Report
- Keywords:
Acromegaly;
Type 2 diabetes mellitus
- MeSH:
Acromegaly;
Adult;
Diabetes Mellitus;
Diabetes Mellitus, Type 1;
Diabetes Mellitus, Type 2;
Glucose;
Growth Hormone;
Humans;
Insulin Resistance;
Joints;
Pituitary Neoplasms
- From:Endocrinology and Metabolism
2012;27(4):318-322
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Acromegaly is generally caused by a benign growth hormone (GH)-secreting pituitary adenoma. It is characterized by a wide range of complications; cardiovascular, respiratory, bone and joint, and metabolic complications. Among them, impaired glucose tolerance and diabetes mellitus, due to GH-induced insulin resistance, has been reported in approximately 16-46% and 19-56%. They are usually improved following the treatment of acromegaly, surgical or medical therapy. We report a first case of 36-year-old man who was paradoxically diagnosed with GAD antibody positive latent autoimmune diabetes in adults (LADA) after the surgical cure of acromegaly.
