Research progress on detection methods for human respiratory syncytial virus
10.3760/cma.j.cn112150-20240108-00024
- VernacularTitle:人呼吸道合胞病毒检测方法的研究进展
- Author:
Na WANG
1
;
Hai LI
;
Jingjing SONG
;
Jinhua SONG
;
Yan ZHANG
Author Information
1. 传染病溯源预警与智能决策全国重点实验室 国家卫生健康委医学病毒和病毒病重点实验室 中国疾病预防控制中心病毒病预防控制所，北京 102206
- Keywords:
Human respiratory syncytial virus;
Antigen detection;
Nucleic acid detection;
Antibody detection;
Virus isolation
- From:
Chinese Journal of Preventive Medicine
2024;58(8):1143-1149
- CountryChina
- Language:Chinese
-
Abstract:
Human respiratory syncytial virus (HRSV) can infect individuals of all ages, with children under five years old, the elderly, and immunocompromised persons as the main high-risk groups. Although older children and adults often exhibit mild or no symptoms, they may still be potential carriers of the virus. Therefore, employing efficient, accurate, and rapid detection methods to timely identify infection sources and quickly halt transmission is an important means to curb the potential spread of the epidemic. However, the clinical manifestations of HRSV infection are difficult to distinguish from acute respiratory infections caused by other respiratory viruses, and the identification relies on the results of pathogen testing. This article summarizes four commonly used detection methods for HRSV based on detection principles: antigen detection, nucleic acid testing, antibody detection, and virus isolation. The advantages, disadvantages, principles, and applicable scenarios of these four methods are summarized and compared. Furthermore, the research progress and prospects of HRSV detection methods are reviewed.
