Bibliometric visualization analysis of thiamine-responsive megaloblastic anemia syndrome
10.3760/cma.j.cn112150-20240109-00033
- VernacularTitle:硫胺素响应性巨幼细胞贫血综合征的文献计量可视化分析
- Author:
Lulan GAO
1
;
Faquan LIN
Author Information
1. 广西医科大学第一附属医院检验科，广西高校临床检验诊断学重点实验室，南宁530021
- Keywords:
Thiamine-responsive megaloblastic anemia syndrome;
Bibliometric visualization analysis;
Solute carrier family 19 member 2
- From:
Chinese Journal of Preventive Medicine
2024;58(7):1069-1075
- CountryChina
- Language:Chinese
-
Abstract:
Visual analysis of the current status, research hotspots, evolving trends, and future prospects in the field of thiamine-responsive megaloblastic anemia syndrome (TRMA), providing new insights and directions for subsequent research on the pathogenic mechanisms and prevention strategies of TRMA. Taking the core database of Web of Science as the literature source, selecting TRMA-related literature records published from 1997 to 2023 as the research object, and using R software and Citexs database to conduct visual analysis and discussion of the research content. The results showed that a total of 89 publications related to the topic were published from 1997 to 2023, with an average annual publication volume of 3 papers. Classified by country, it was found that the United States, and Israel among other countries and institutions, published a significant number of papers. Through keyword frequency analysis, high frequencies of keywords such as diabetes, deafness, thiamine-responsive megaloblastic anemia, and mutations in the solute carrier family 19 member 2 (SLC19A2) gene were observed, indicating that to date, these keywords have been the main research directions, highlighting a gradually reached consensus on the mechanism exploration of TRMA. In conclusion, TRMA research focuses on the mechanisms of hot topics such as diabetes, deafness, and thiamine-responsive megaloblastic anemia, and the core gene SLC19A2 research may currently become a new breakthrough point for future molecular studies.
