Research progress of common respiratory virus receptor binding sites
10.3760/cma.j.cn112150-20230911-00175
- VernacularTitle:常见呼吸道病毒受体结合位点的研究进展
- Author:
Huanzi PENG
1
;
Jing LI
;
Yunhao LI
;
Yingqian XU
;
Jiaqi PENG
;
Xiaobing XIE
Author Information
1. 湖南中医药大学第一附属医院医学检验与病理中心，长沙410007
- Keywords:
Respiratory virus;
Receptor;
Coronavirus;
Angiotensin-converting enzyme 2
- From:
Chinese Journal of Preventive Medicine
2023;57(12):2212-2219
- CountryChina
- Language:Chinese
-
Abstract:
Respiratory viral infections are an important public health problem worldwide, with complex mechanisms of infection, and the key to infection lies in the specific binding between respiratory viruses and receptors. This article provides an overview of the progress in the study of receptors for respiratory viruses, such as coronavirus and influenza virus (IV), with a focus on the binding sites of receptors such as angiotensin-converting enzyme 2 (ACE2) and sialic acid (SA) to respiratory viruses and the role of receptor diversity in respiratory viral infections. An in-depth study of the binding sites between viruses and receptors will help to understand the molecular mechanism of respiratory viral infections and provide a theoretical basis for disease prevention and control and the development of new therapeutic targets.
