Research and development technology platform and research progress of universal influenza vaccine
10.3760/cma.j.cn112150-20210125-00075
- VernacularTitle:流感通用疫苗研发技术平台与研究进展
- Author:
Tao DENG
1
;
Jiayou ZHANG
;
Xiaoming YANG
Author Information
1. 武汉生物制品研究所病毒性疫苗研究二室 430207
- Keywords:
Influenza vaccine;
Influenza, human;
Universal influenza vaccine
- From:
Chinese Journal of Preventive Medicine
2021;55(12):1500-1506
- CountryChina
- Language:Chinese
-
Abstract:
Vaccination is the most effective measure to prevent influenza. However, due to the existence of antigen drift and/or antigen shift of influenza virus, the vaccine strains often do not match the epidemic strains, so that the protection provided by influenza vaccine is still limited. With the rapid development of new vaccine technology, a kind of influenza vaccine with extensive protection or universal has attracted great attention. It can effectively induce humoral and cellular immunity against the conserved epitopes of influenza virus, provide good protection against various types/subtypes of influenza virus, and has a rapid production platform, which is the ideal goal for the development of a new generation of universal influenza vaccine. This article reviews the latest research progress of influenza universal vaccine.
