The role of the traditional surgical procedures for gastroesophageal reflux disease cannot be ignored
10.3760/cma.j.cn112139-20200224-00125-1
- VernacularTitle:传统外科手术治疗胃食管反流病不容忽视
- Author:
Jinghai ZHOU
1
;
Qunyou TAN
Author Information
1. 陆军军医大学大坪医院胸外科，重庆 400042
- Keywords:
Gastroesophageal reflux;
Regurgitation, Gastric;
Esophagitis, Peptic;
Fundoplication
- From:
Chinese Journal of Surgery
2020;58(9):672-676
- CountryChina
- Language:Chinese
-
Abstract:
Gastroesophageal reflux disease (GERD) is a common digestive disease with characteristics of a multitude of pathogenesis, a variety of clinical manifestations and a strong negative impact on physical and mental health of the patients. GERD is classified into non-erosive reflux disease and reflux esophagitis in terms of absence or presence of mucosal damage at endoscopic findings. Proton pump inhibitors (PPI) are widely used in the treatment of GERD, especially for patients with non-erosive reflux disease or mild reflux esophagitis. However, PPI do not affect pathophysiologic mechanisms of GERD or reduce the number of reflux events. When PPI fails to adequately control the symptoms of GERD as a result of gastroesophagel junction structural defects, the antireflux surgical procedures are indicated to create a mechanical barrier to reflux. The laparoscopic fundoplication remains the most commonly performed and is the current "gold-standard" anti-reflux procedure. The outcomes of the antireflux surgical procedures are superior to medical therapy for GERD in light of subjective symptoms, objective examinations, quality of life and patient satisfaction. As of now, enough attention has not been paid to the traditional surgical procedures of GERD in China. It is controversial about which is optimal among the three major types of procedures, selection should be tailored to classification, mechanism, age, mental status and esophageal motility. GERD is a chronic disease and either medical or surgical therapy may put the patient at different risk, therefore the patient′s preferences should be considered adequately before choosing the treatment protocols.
