Current status of research on short-term quality of life after sphincteric-saving surgery in rectal cancer patients
10.3760/cma.j.cn.441530-20190525-00219
- VernacularTitle:直肠癌保肛术后短期生活质量研究现状
- Author:
Jiale GAO
1
;
Yongbo AN
;
Dong WANG
;
Hongwei YAO
;
Zhongtao ZHANG
Author Information
1. 首都医科大学附属北京友谊医院普通外科 国家消化系统疾病临床医学中心 肿瘤侵袭和转移机制研究北京市重点实验室 100050
- Keywords:
Rectal neoplasms;
Sphincteric-saving surgery;
Quality of life
- From:
Chinese Journal of Gastrointestinal Surgery
2020;23(4):415-420
- CountryChina
- Language:Chinese
-
Abstract:
Sphincteric-saving surgery (SSS) is currently a hot spot in the treatment of mid-low rectal cancer. Although it preserves the anatomical continuity of the colon and anus, the postoperative functional outcomes and quality of life (QOL) remains to be confirmed. Current studies have shown that quality of life worsens at the first month after surgery, improves within 3-6 months, and stabilizes at about 1 year. The QOL was associated with patient-related factors, tumor-related factors, treatment-related factors and postoperative complications. For patient-related factors, younger patients have worse role function and sexual function but better cognitive function and physical function. Male patients deteriorate significantly in sexual and social function. For tumor-related factors, patients with lower rectal cancer have poorer defecation function. Those with advanced rectal cancer are more likely to suffer from side-effects related to chemotherapy. For treatment-related factors, patients undergoing intersphincteric resection have worse role function, body image and sexual interest. Preventive ileostomy results in the deterioration of role function, body image and sexual interest. Chemotherapy causes taste changes and chest pain. For postoperative complication, patients with anastomotic leakage have worse bowel function and psychological state. Patients with major low anterior resection syndrome and genitourinary dysfunction have worse global health score, social function and role function. In conclusion, short-term quality of life after sphincteric-saving surgery is acceptable. To improve QOL, specific intervention and guidance should be given to patients in this stage. Meanwhile, since many factors influence the quality of life simultaneously, researchers are confused about the questionnaire outcomes. Therefore, more specific and comprehensive tools are needed to evaluate QQL after sphincteric-saving surgery.
