Effect of esomeprazole combined with mosapride on treating patients with reflux esophagitis
- VernacularTitle:埃索美拉唑与莫沙必利联用对反流性食管炎患者的影响
- Author:
Jianmei JIANG
1
Author Information
- Keywords: reflux esophagitis; mosapride; esomeprazole; quality of life
- From: Journal of Clinical Medicine in Practice 2018;22(5):108-110
- CountryChina
- Language:Chinese
- Abstract: Objective To study effect of esomeprazole combined with mosapride for patients with reflux esophagitis.Methods A total of 200 patients with reflux esophagitis in our hospital were divided into two groups according to different treatment methods.The control group (n =80) took mosapride combined with omeprazole for treatment,while the study group (n =120) took esomeprazole combined with mosapride for treatment.Clinical effect,adverse reaction,and acid reflux and heartburn scores before and after treatment,life quality score of two groups were observed.Results The study group had higher total efficiency (P ＜0.05),and lower incidence of adverse reactions than the control group (P ＜ 0.05).Before treatment,typical symptoms including heartburn and acid reflux had no significant differences (P ＞ 0.05),but study group was lower than the control group in above indicators (P ＜ 0.05);Before treatment,quality of life scores have no significant difference in two groups (P ＞ 0.05),but the study group after treatment was significantly higher than the control group (P ＜ 0.05).Conclusion Esomeprazole combined with mosapride treatment not only can improve the clinical effect,and enhance clinical symptoms and quality of life scores,but can reduce adverse reactions and improve safety,so it is worthy of promotion.
