Clinical study of 50 neonates with mechanical ventilation complicated with respiratory tract infection
- VernacularTitle:50例新生儿机械通气并发呼吸道感染的临床研究
- Author:
Zhengping XU
1
Author Information
- Keywords: mechanical ventilation; respiratory tract infection; pathogens; gestational age; drug sensitivity test
- From: Journal of Clinical Medicine in Practice 2018;22(5):49-51
- CountryChina
- Language:Chinese
- Abstract: Objective To study the clinical situation of neonates with mechanical ventilation complicated with respiratory tract infection.Methods Fifty neonates treated in our hospital were selected,and the difference of respiratory tract infection patients were compared,and pathogen of the respiratory tract infection of neonates was culture,and cultured pathogen was analyzed.Results Out of 50 neonates with respiratory tract infection,32 cases (64.00％) occurred respiratory tract infection.The pathogen and drug sensitivity test showed there were six pathogens,among which Escherichia coli,Klebsiella pneumoniae,Pseudomonas aeruginosa were commonly seen,but there was no significant difference among these pathogens (P ＞ 0.05).Gram-negative bacteria was more common,drug susceptibility results showed that it had higher sensitivity to ciprofloxacin,imipenem.Newborns with 3 ～7 d,＞ 7 d mechanical ventilation had higher respiratory tract infection than those with ＜ 1 d,1 ～ 3 d (P ＜ 0.05).The incidence of respiratory tract infection in premature infants was higher than that in full term infants,but there was no significant difference between the two groups (P ＞ 0.05).After antibiotics and symptomatic treatment,34 cases were cured,14 cases quitted the treatment due to severe illness or economic pressure,and 2 patients were died (P ＞ 0.05).Conclusion The pathogenesis of respiratory tract infection is mainly Gram-negative bacteria,and the incidence of respiratory infection is closely correlated to time of mechanical ventilation.Therefore,drug sensitivity test,antibiotics application should be done in clinic,and the ventilator can be evacuated as soon as possible.
