Effect of metformin combined with acupoint therapy with low frequency impulse stimulation on repairing neuropathy of patients with diabetic foot
10.7619/jcmp.201803012
- VernacularTitle:二甲双胍联合低频脉冲刺激穴位疗法对糖尿病足患者神经病变的修复效果
- Author:
Hongmei XUAN
1
;
Liyan XING
;
Jinyu DU
Author Information
1. 北京市昌平区医院内分泌科
- Keywords:
metformin;
acupoint therapy with low frequency impulse stimulation;
diabetic foot;
neuropathy
- From:
Journal of Clinical Medicine in Practice
2018;22(3):44-47
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of metformin combined with acupoint therapy with low frequency impulse stimulation on repairing diabetic neuropathy of patients with diabetic foot.Methods Totally 150 diabetic foot patients with neuropathy were randomly divided into observation group (n =75) and control group (n =75).The therapeutic effect,nerve conduction velocity,fasting blood glucose,postprandial 2 h blood glucose,glycosylated hemoglobin and adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 92％,which was significantly higher than 76％ of the control group (P ＜0.05).The SCV and MCV of the tibial nerve and peroneal nerve increased significantly after treatment in all the patients (P ＜0.05),and the SCV and MCV of the tibial nerve and peroneal nerve in the observation group were significantly higher than those in the control group (P ＜ 0.05).After treatment,the levels of HbA1 C,FBG and 2 hPBG decreased significantly when compared with those before treatment (P ＜ 0.05),and the levels of HbA1 C,FBG and 2 hPBG in the observation group were significantly lower than those in the control group (P ＜ 0.05).The total incidence rate of complications in the observation group was 8％,which was significantly lower than 20％ in the control group (P ＜ 0.05).Conclusion Metformin combined with acupoint therapy with low frequency impulse stimulation can effectively improve the symptoms of neuropathy in patients with diabetic foot.
