Effects of hemodialysis combined with hemoperfusion on expression of β2-microglobulin and high-sensitivity C-reactive protein in patients with uremia
10.7619/jcmp.201705018
- VernacularTitle:血液透析联合血液灌流对尿毒症患者β2-微球蛋白和超敏C反应蛋白的影响
- Author:
Shihui ZHANG
1
;
Yan ZHANG
;
Xi TANG
Author Information
1. 四川省成都市第六人民医院肾病科
- Keywords:
hemodialysis;
hemoperfusion;
uremia;
β2-microglobulin;
high-sensitivity C-reactive protein
- From:
Journal of Clinical Medicine in Practice
2017;21(5):65-67
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of hemodialysis combined with hemoperfusion on the expression of β2-microglobulin (β2-MG) and high-sensitivity C-reactive protein (hs-CRP) in patients with uremia.Methods A total of 50 patients with uremia were randomly divided into control group and observation group.The control group was treated by single hemodialysis,while the observation group was treated by hemodialysis combined with hemoperfusion.After the first treatment and 2 months after treatment,the levels of β2-MG and hs-CRP were detected.Results After the first treatment and 2 months after treatment,the levels of β2-MG and hs-CRP in the observation group were significantly lower than those before treatment,and were significantly lower than those in the control group (P ＜ 0.05).Conclusion Hemodialysis combined with hemoperfusion can reduce the levels of β2-MG and hs-CRP in patients with uremia.
