Scleroma of the Larynx: A Case Report.
- Author:
Hun Soo KIM
1
;
Seok Won PARK
;
Jin Man KIM
Author Information
1. Department of Pathology, Chungnam National University School of Medicine, Daejeon, Korea. jinmank@cnu.ac.kr
- Publication Type:Case Report
- Keywords:
Larynx;
Scleroma;
Mikulicz Cell;
Warthin;
Starry Stain
- MeSH:
Coloring Agents;
Cytoplasm;
Diagnosis;
Emergencies;
Female;
Humans;
Laryngeal Neoplasms;
Laryngoscopy;
Larynx*;
Microscopy, Electron;
Middle Aged;
Nasal Mucosa;
Physical Examination;
Plasma Cells;
Rhinoscleroma
- From:Korean Journal of Pathology
2003;37(4):287-290
- CountryRepublic of Korea
- Language:English
-
Abstract:
Scleroma of the larynx is a rare specific granulomatous disease and is usually presented as alaryngeal extension of a primary rhinoscleroma. We report an unusual case of laryngeal scleromain a 64-year-old female patient whose presented with progressive upper respiratory obstructivesymptoms lasted for 2 years. Symptoms were acutely exaggerated during the course of one month.On physical examination, the nasal mucosa was atrophic and crusted, and septal perforationwas noted. The fiberoptic laryngoscopy revealed a yellowish granulated epiglottic mass with adirty surface mimicking laryngeal cancer. Histological sectioning showed the characteristic featuresof scleroma including Mikulicz cells with scattered plasma cells and some neutrophils.Warthin-starry stains and electron microscopy examination showed numerous short rods insidethe cytoplasm of the Mikulicz cells. After the diagnosis, the patient underwent an emergency tracheostomyfollowed by long-term antibiotic treatment, and her symptoms have slowly improved.
