Mechanism of soft palate muscle regeneration after cleft palate surgery
10.3760/cma.j.cn114453-20220805-00240
- VernacularTitle:腭裂术后软腭肌肉再生的机制
- Author:
Guiying LI
1
;
Di WU
Author Information
1. 中国医学科学院北京协和医学院整形外科医院唇腭裂整形科，北京 100144
- Keywords:
Cleft palate;
Muscle regeneration;
Satellite cells;
Fibrosis;
Tissue engineering
- From:
Chinese Journal of Plastic Surgery
2023;39(12):1366-1370
- CountryChina
- Language:Chinese
-
Abstract:
Cleft palate is one of the most common oral and maxillofacial deformities, which can be treated through surgery. Compared to other skeletal muscles, the soft palate muscles have a lower regenerative capacity, and tend to develop more fibrosis than other skeletal muscles. It is difficult to achieve the best desired improvement in the function of the soft palate muscles after cleft palate surgery. In addition, satellite cells, which are considered as muscle stem cells, also play an important role in the process of soft palate muscle regeneration. This article will discuss the mechanism of the soft palate muscle regeneration after cleft palate surgery and the accompanying fibrosis process. It will also analyze the factors that affect the regeneration of soft palate muscles and summarize the corresponding methods to improve the muscle regeneration function after cleft palate surgery.
