Effect of vacuum sealing drainage combined with hydrogen peroxide irrigation in the treatment of venous leg ulcer
10.3760/cma.j.cn114453-20210630-00279
- VernacularTitle:负压封闭引流联合过氧化氢溶液冲洗在下肢静脉溃疡的应用
- Author:
Zhong CHEN
1
;
Jiqiong WANG
;
Weiren LI
Author Information
1. 贵州医科大学附属医院整形烧伤外科，贵阳 550004
- Keywords:
Varicose ulcer;
Wounds and injuries;
Hydrogen peroxide;
Vacuum sealing drainage;
Irrigation
- From:
Chinese Journal of Plastic Surgery
2022;38(2):180-185
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the effect of vacuum sealing drainage(VSD)combined with hydrogen peroxide irrigation in the treatment of venous leg ulcer (VLU).Methods:The clinical data was focused on the cases with venous leg ulcer, who were treated by the Department of Plastic and Burn Surgery, Affiliated Hospital of Guizhou Medical University from January 2014 to March 2021. According to the treatment method, patients were divided into two groups. After debridement, the intervention group was irrigated with VSD combined with hydrogen peroxide, while the control group was irrigated with VSD combined with normal saline . The duration of VSD treatment was recorded, and the effective rate of wound treatment was calculated. According to the treatment situation, the medium thickness skin graft was performed, and the good survival rate of skin graft was calculated.Results:A total of 55 patients were enrolled in this study. Aged 35 to 86 years old, including 32 males and 23 females. Before the procedure, all the above patients underwent pathological examination to exclude the ulcers caused by malignant tumors. There were 34 cases in the intervention group and 21 cases in the control group. The duration of VSD treatment in the intervention group was (8.53±1.52) d, and that in the control group was (10.33±3.25) d, and the difference was statistically significant ( t=2.39, P=0.025). The effective rate of wound assessment was 82.35% (28/34) in the intervention group and 57.14% (12/21) in the control group; the difference was statistically significant ( χ2=4.16, P=0.041). The good survival rate of skin graft was 91.18% (31/34) in the intervention group and 61.90% (13/21) in the control group; the difference was statistically significant ( χ2=5.24, P=0.022). Conclusions:VSD combined with hydrogen peroxide irrigation is an effective method to treat VLU, which can shorten the preparation time of wounds and improve the survival rate of skin grafts.
