Clinical comparative study of different energy pulsed dye laser treating the hypertrophic scar
10.3760/cma.j.cn114453-20200713-00416
- VernacularTitle:不同能量密度脉冲染料激光治疗增生性瘢痕的效果比较
- Author:
Jing CHENG
1
;
Li YANG
;
Na LI
;
Juntao HAN
;
Dahai HU
Author Information
1. 空军军医大学西京医院全军烧伤中心烧伤与皮肤外科，西安 710032
- Keywords:
Lasers, dye;
Hypertrophic scar;
Energy density;
Vancouver Scar Scale;
Patient satisfaction
- From:
Chinese Journal of Plastic Surgery
2021;37(6):599-605
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the efficacy and safety of low energy and high energy density pulsed dye laser in treating hypertrophic scars.Methods:From January 2019 to March 2019, forty-five patients with hypertrophic scar were randomly divided into three groups with 15 cases in each group: the control group, low energy density group and high energy density group. There were 26 males and 19 females, aged from 1 to 48 years. Each patient was treated with compressive treatment and drug treatment. The patients in low energy density group were treated with 595 nm pulsed dye laser and the energy density was 4.0-6.5 J/cm 2; the patients in high energy density group were treated with 595 nm pulsed dye laser and the energy density was 6.6-9.0 J/cm 2; the patients in control group were not treated with laser. Patients were treated with pulsed dye laser once every 3-4 weeks until 6 months. Scars were scored by Vancouver scar scale (VSS) before and after treatment. Degree of satisfaction of patients and adverse reactions were also recorded. Date were processed with one-way analysis of variance, χ2 test and t test. Results:(1) VSS scores in both control group and high energy group after treatment were significantly higher than those before treatment. VSS scores in low energy group after treatment were significantly lower than those before treatment ( P<0.05); VSS score in all three groups were significantly different after treatment( P<0.05). (2) Color scores in control and high energy group after treatment were higher than those before treatment in the same group. Color scores in low energy group after treatment were lower than those before treatment( P<0.05). Color scores in these three groups were significantly different( P<0.05). (3) The satisfaction degree of patients in control group was 6.67%(1/15), 13.33%(2/15) in high energy density group and 66.67%(10/15) in low energy density group. The satisfaction degree in low energy density group is significantly higher than that in control group and high energy density group ( P<0.05). (4) The duration of erythema or purpura in low energy density group after treatment was significantly shorter than that in high energy density group( P<0.05). No patient had blister in low energy density group, compared to 10 patients in high energy density group, the cases of adverse reaction in high energy density group was significantly more than that in low energy density group. Conclusions:The low energy density pulsed dye laser in the treatment of hypertrophic scar is better than high energy density pulsed dye laser, and the incidence of adverse reactions is low. Low energy density(4.0~6.5 J/cm 2) pulsed dye laser is the recommended energy parameter for the treatment of hypertrophic scar.
