Acute kidney injury caused by acute dimethyl oxalate poisoning: a case report
10.3760/cma.j.cn121094-20230808-00026
- VernacularTitle:急性草酸二甲酯中毒导致急性肾损伤1例
- Author:
Yuxia LI
1
;
Jiarong ZHANG
;
Yanjun FENG
Author Information
1. 定西市人民医院肾病科，定西 743000
- Keywords:
Poisoning;
Dimethyl oxalate;
Acute kidney injury;
Blood purification;
Hemodialysis
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2024;42(8):604-608
- CountryChina
- Language:Chinese
-
Abstract:
Dimethyl oxalate is one of the occupational toxic chemicals and causes strong renal toxicity. On May 16, 2023, a patient with acute dimethyl oxalate poisoning was admitted to Dingxi People's Hospital. The patient presented with nausea, vomiting, lumbar distension, weakness, poor appetite, anuria, and rapidly progressing acute kidney injury. Renal biopsy confirmed acute oxalate nephropathy. After symptomatic supportive treatments such as blood purification, anti-oxidative stress, glucocorticoid, fluid supplementation, alkalized urine, anti-infection, controlling blood pressure, calcium supplementation and anemia correction, the patient's symptoms disappeared, and the kidney function basically returned to normal. This case suggested that the etiology of patients with acute kidney injury must be clearly identified, and renal biopsy was an important examination method. For patients suffering from acute dimethyl oxalate poisoning, comprehensive treatment based on blood purification should be performed as soon as possible, aiming to improve the prognosis.
