Isolation of the Causative Microorganism and Antimicrobial Susceptibility of Impetigo.
- Author:
Woo Joong KIM
1
;
Kyung Real LEE
;
Sang Eun LEE
;
Hee Jung LEE
;
Moon Soo YOON
Author Information
1. Department of Dermatology, CHA Bundang Medical Center, CHA University, Seongnam, Korea. msch11@chamc.co.kr
- Publication Type:Original Article
- Keywords:
Antibiotics susceptibility;
Impetigo;
MRSA;
Staphylococcus aureus
- MeSH:
Acetamides;
Acinetobacter baumannii;
Anti-Bacterial Agents;
Bacteria;
Bacterial Infections;
Candida albicans;
Ciprofloxacin;
Clindamycin;
Dibekacin;
Enterococcus;
Enterococcus faecalis;
Enterococcus faecium;
Erythromycin;
Gentamicins;
Humans;
Impetigo;
Incidence;
Klebsiella oxytoca;
Methicillin Resistance;
Methicillin-Resistant Staphylococcus aureus;
Oxazolidinones;
Penicillins;
Prevalence;
Staphylococcus aureus;
Streptococcus;
Teicoplanin;
Tetracycline;
Trimethoprim, Sulfamethoxazole Drug Combination;
Vancomycin;
Linezolid
- From:Korean Journal of Dermatology
2012;50(9):788-794
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Impetigo is a common bacterial infection caused by Staphylococcus aureus, and group A beta-hemolytic Streptococcus or both. Recently, S. aureus has been reported as the most frequently isolated pathogen of impetigo and the incidence of methicillin-resistant S. aureus (MRSA) among patients with impetigo has increased. OBJECTIVE: To investigate the predominant microorganism and the antibiotic susceptibility of the impetigo causative pathogen. METHODS: Bacterial culture and antimicrobial susceptibility testing were performed in patients with impetigo from June 2006 to May 2012. RESULTS: Of 164 patients, bacteria were cultured from 139 patients. Among them, S. aureus was isolated from 114 (82%) patients. The others were Acinetobacter baumannii, Enterobactercloacae, Enterococcus species, Enterococcus faecium, Enterococcus faecalis, Klebsiella oxytoca, and Candida albicans. The resistance rates of S. aureus against antibiotics were as follows: penicillin, 95.6%; erythromycin, 43.9%; fusidicacid, 38.1%; clindamycin, 24.5%; gentamycin, 21%; tetracycline, 12.3%; trimethoprim-sulfamethoxazole, 0.9%; ciprofloxacin, 0%; habekacin, 0%; linezolid, 0%; teicoplanin, 0%; and vancomycin, 0%. Thirty-four (29.8%) S. aureus isolates were MRSA, and the prevalence of MRSA increased during the 6-year period. CONCLUSION: The most predominant pathogen in impetigo was S. aureus, which was sensitive to ciprofloxacin, habekacin, linezolid, trimethoprim-sulfamethoxazole, teicoplanin, and vancomycin. An increase in the prevalence of MRSA was observed during the 6-year period, and the effective antibiotics for MRSA were trimethoprim-sulfamethoxazole, teicoplanin and vancomycin.
