Determination of chloroacetic acid in workplace air by silanization-gas chromatography
10.3760/cma.j.cn121094-20200603-00320
- VernacularTitle:工作场所空气中氯乙酸硅烷化-气相色谱法
- Author:
Peng WANG
1
;
Hong REN
;
Qiuliang XU
;
Yiyao CAO
Author Information
1. 310051 杭州，浙江省疾病预防控制中心
- Keywords:
Chromatography, gas;
Chloroacetic acid;
Workplace;
Air;
Silanization
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2021;39(4):299-302
- CountryChina
- Language:Chinese
-
Abstract:
Objective:A method to determine acrylic acid in workplace air was developed by silanization-gas chromatography.Methods:In March 2020, chloroacetic acid in air were absorbed by silica gel tube, the samples were dried, then were desorbed and silanized by acetonitrile: N, O-bis (trimethylsilane) trifluoroacetamide (2∶1, V/V) at room temperature, allowed quantitative analysis of chloroacetic acid as its silanization product by gas chromatography.Results:Calibration curve of the method was linear within the range 0-162.8 μg/ml and showed good linearity with linear equation: y=0.011 8 x, r=0.999 7. The determination limit of the method was 0.8 μg/ml, and the minimum detection concentration was 0.05 mg/m 3 (collect 15 L air) . The relative standard deviation ( RSD) was 0.5%-1.3% ( n=5) . Recoveries were between 98.6%-101.2%. Conclusion:The results prove silanization-gas chromatography is an accurate, simple and high sensitive method for determining chloroacetic acid in workplace air.
