Advances in the cytotoxic mechanism of nanomaterials graphene oxide
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.cn121094-20200221-00073
   		
        
        	
        		- VernacularTitle:纳米材料氧化石墨烯的细胞毒性机制研究进展
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yihan GAN
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Shibo YING
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 310013 杭州医学院职业病防治研究所
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Cytotoxicity;
			        		
			        		
			        		
				        		Graphene;
			        		
			        		
			        		
				        		Graphene oxide;
			        		
			        		
			        		
				        		Nanomaterials;
			        		
			        		
			        		
				        		Occupational health
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Industrial Hygiene and Occupational Diseases
	            		
	            		 2021;39(3):237-240
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Graphene oxide is a novel two-dimensional carbon nanomaterial, but it has potential risks for the health of occupationally exposed workers. This article briefly reviews the research progress on the cytotoxic mechanism of graphene oxide and its derivatives in terms of oxidative stress, physical damage and dysfunction of enzyme activity. This review also discusses effective measures for the mitigation of cytotoxicity in order to provide helpful evidence for occupational health risk and biological safety assessment of graphene nanomaterials in China.