Advances in flavoring-related bronchiolitis obliterans
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.cn121094-20191104-00513
   		
        
        	
        		- VernacularTitle:双乙酰香味剂相关性闭塞性细支气管炎的研究进展
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yuanying WANG
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Qiao YE
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 100020 北京,首都医科大学附属北京朝阳医院职业病与中毒医学科,间质性肺疾病临床诊疗与研究中心
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Bronchiolitis, obliterans;
			        		
			        		
			        		
				        		Diacetyl flavoring;
			        		
			        		
			        		
				        		2, 3-Butanedione;
			        		
			        		
			        		
				        		Occupational diseases;
			        		
			        		
			        		
				        		Risk factors
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Industrial Hygiene and Occupational Diseases
	            		
	            		 2020;38(9):717-720
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Occupational exposure to the diacetyl flavoring may cause bronchiolitis obliterans (BO) in workers. The first case of flavoring-related bronchiolitis obliterans was reported in 2002. Since then, similar cases have been identified among workers in various production industries in some countries and regions. At present, there are no cases reported in China. In order to improve the awareness of the disease and promote the prevention work, this article reviews the research progress of case recognition, risk factors, clinical manifestation and possible pathogenesis.