Neuropad test for sudomotor function to predict the risk of diabetic foot ulceration
10.3969/j.issn.1673-4254.2014.04.26
- VernacularTitle:欧米诺汗印法对糖尿病足溃疡发生风险的预测价值
- Author:
Yan QIN
1
;
Ying CAO
;
Fang GAO
;
Xiangrong LUO
;
Jimin LI
;
Xiajun FU
;
Yaoming XUE
Author Information
1. 南方医科大学南方医院内分泌代谢科
- Keywords:
Neuropad;
Sudomotor function;
Diabetic foot ulceration
- From:
Journal of Southern Medical University
2014;(4):560-562
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the predictive value of Neuropad test on occurrence of diabetic foot ulceration (DFU) among type 2 diabetic patients. Methods We divided 725 cases of type 2 diabetic patients into the high-risk and the non-high-risk groups of DFU based on the results of vibration perception thresholds(VPT) examination, which was widely used as a criteria for predicting DFU. Receiver operating characteristic (ROC) analysis was used to compare the effectiveness of Neuropad with 10 g Semmes-Weinstein monofilament (10 g SWMF) testing in predicting the risk of DFU. Results Among 725 patients of type 2 diabetes, 6.1% were at a high risk of DFU. Compared to non-high-risk group, patients in high-risk group had older age, longer diabetes duration, higher values of complete colour change time (CCC time) of Neuropad and higher abnormal rate of 10 g SWMF (P<0.01). CCC time of Neuropad was shown to be better in predicting the risk of DFU than 10 g SWMF, and the area under the ROC curve was about 0.8, and the best cut-off value was 22.25 min. Conclusion Neuropad is an effective means for predicting of the risk of DFU, and can be used to prevent diabetic foot ulceration.
