Analysis of inter room comparison results of internal quality control data for maternal serological prenatal screening in Jiangsu Province from 2021 to 2022
10.3760/cma.j.cn112150-20231219-00460
- VernacularTitle:2021—2022年江苏省母血清学产前筛查室内质控数据的室间比对结果分析
- Author:
Ying ZHANG
1
;
Honglei DUAN
;
Jie LI
;
Zhijun JIA
Author Information
1. 南京大学医学院附属鼓楼医院产前诊断中心，南京210008
- Keywords:
Serological screening;
Quality control;
Interventricular comparison analysis
- From:
Chinese Journal of Preventive Medicine
2024;58(3):358-363
- CountryChina
- Language:Chinese
-
Abstract:
The relevant data reported by laboratories carrying out serological prenatal screening in Jiangsu Province from 2021 to 2022 were retrospectively analyzed, and the provincial inter-ventricular quality assessment was realized by comparing the internal quality control data of laboratories. The quality control analysis platform of prenatal screening in Jiangsu Province was used to collect the determination methods, quality control data results of three concentrations, instrument platform, reagents and other relevant information of maternal serological screening quality control in early and middle pregnancy in each laboratory from 2021 to 2022. Firstly, the test results of each laboratory were statistically analyzed, and the precision of each laboratory was evaluated by the variation coefficient of indoor quality control. Secondly, the consistency was evaluated by comparing laboratories with different experimental platforms. The results showed that the passing rate of PAPP-A(pregnancy-associated plasma protein-A) precision test in 2021 and 2022 was 87.5% (7/8) and 92.3% (12/13), respectively. The accuracy pass rate of the Free β-hCG (free beta-human chorionic gonadotrophin)(early pregnancy) test in 2021 and 2022 was 97.5% (39/40) and 95.5% (42/44), and the accuracy pass rate of the AFP(alpha-fetal protein) test in 2021 and 2022 was 100% (40/40) and 90.9% (40/44), respectively. The accuracy pass rate of Free β-hCG (middle pregnancy) test in 2021 and 2022 was 100% (40/40) and 95.5% (42/44), respectively. The consistency of each index was 100%. In conclusion, the relevant data reported by laboratories carrying out serological prenatal screening in Jiangsu Province has a high consistency, and for a small number of laboratories with poor stability, it is necessary to make periodic evaluation and rectification according to the data analysis results, so as to improve the quality control management of maternal serological prenatal screening.
